Introduction

Fucoxanthin is a carotenoid isolated from seaweeds. Emerging research studies have reported that this carotenoid has a significant number of physiologically and biologically beneficial properties to offer. In addition, it has an overall profile that makes it suitable for inclusion in medicinal and nutritional products intended to prevent and treat chronic diseases. Furthermore, Fucoxanthin's safety as a pharmaceutical ingredient has been established already. Hence, we can discuss its pharmacological activities in this brief and see the health benefits this normally-found-in-sea-moss carotenoid offers for human health.

Anti-Obesity

Obesity is one of the biggest health challenges right now. There are multiple ways in which fucoxanthin can counter the problem of obesity. For example, one of the research studies showed that it significantly reduced plasma and hepatic triglyceride concentrations and cholesterol levels. In another study, it affected the gene expression associated with lipid metabolism, ultimately loading the potential lipid content3.

Diabetes

Diabetes typically results from consumption of nutritionally rich diets and certain irregular dietary habits. A research study found that fucoxanthin can decrease the insulin resistance by increasing ratio of certain enzymes and glycogen content.

Cancer

Chemotherapy is commonly practiced conventional way of countering cancer. But there are serious question marks on the effectiveness of the process since cancer can return. research studies have shown that fucoxanthin can induce cell cycle arrest add a pop ptosis. Hence the compound can be used to control cancerous malignancies.

Metabolism & Gut Health

The metabolism of fucoxanthin varies from human-to-human subjects. The primary active metabolite in this metabolism is fucoxanthin all. Its bioavailability is quite good, throw in the fact that it has antioxidant profile, and you're looking at a very valuable substance for the human body.

Liver Diseases

Fucoxanthin has shown the inhibitory potential when it comes to hepatic oxidative stress inflammation and fibrosis. This was observed in mice model. Furthermore, it has also shown protective effects against alcoholic liver injury. 

Nutraceutical

Nutraceuticals are defined as substances that are food or part of food, providing medical or health benefits as well as contributing towards prevention and treatment of certain diseases or disorders. Looking at the Fucoxanthin’s profile, it is certainly an excellent choice as a nutraceutical. 

Fibrosis

The healing process in which connective tissues replace normal parenchymal tissues, ultimately resulting in the formation of permanent scar tissue is known as fibrosis. Fucoxanthin inhibits fibrosis and diet induced non-alcoholic stay to hepatitis model mice. 

Summary

We have recently seen an alarming surge in fats, sugars, and calories. The situation is further exacerbated by the adoption of a lifestyle devoid of any physical activity whatsoever. This diet and lifestyle combination leads to certain diseases such as obesity, diabetes, cancer, and several other chronic diseases. Researchers are now focusing on finding safe and effective functional ingredients in food which can decrease the risk of such conditions. What we have shared in this brief with you suggests that Fucoxanthin is one of those compounds that can prove to be a game-changer in the world of functional foods in the future. Its presence in sea moss makes its availability super easy. If you don't have any sea moss in your refrigerator, perhaps, it is time to order some from Herbal Vineyard.

References 

1. Fucoxanthin supplementation improves plasma and hepatic lipid metabolism and blood glucose concentration in high-fat fed C57BL/6N mice - PubMed. https://pubmed.ncbi.nlm.nih.gov/20519145/
2. Ha, A. W. & Kim, W. K. The effect of fucoxanthin rich power on the lipid metabolism in rats with a high fat diet. Nutr Res Pract 7, 287–293 (2013)
3. Zhang, H. et al. Fucoxanthin: A Promising Medicinal and Nutritional Ingredient. Evid Based Complement Alternat Med 2015, 723515 (2015).
4. The pathogenesis of obesity - PubMed. https://pubmed.ncbi.nlm.nih.gov/10932674/
5. Zhang, H. et al. Fucoxanthin: A Promising Medicinal and Nutritional Ingredient. Evid Based Complement Alternat Med 2015, 723515 (2015).
6. Takatani, N. et al. Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice. Biochemical and Biophysical Research Communications 528, 305–310 (2020).
7. Kim, M.-B. et al. Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity. Nutrients 14, 2280 (2022).

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